Fluorination methods in drug discovery
نویسندگان
چکیده
منابع مشابه
Computational methods in drug discovery
The process for drug discovery and development is challenging, time consuming and expensive. Computer-aided drug discovery (CADD) tools can act as a virtual shortcut, assisting in the expedition of this long process and potentially reducing the cost of research and development. Today CADD has become an effective and indispensable tool in therapeutic development. The human genome project has mad...
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The application of hypofluorites (fluoroxy-compounds), especially tnfluoromethyl hypofluorite, in the synthesis of fluorinated steroids is described. Hypofluorites are powerful but selective fluorinating agents with unusual electrophilic character. They should find considerable application not only in the synthesis of fluorinated steroids, but for preparation of fluorinated compounds of many di...
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ژورنال
عنوان ژورنال: Organic & Biomolecular Chemistry
سال: 2016
ISSN: 1477-0520,1477-0539
DOI: 10.1039/c6ob00764c